CCL2 at the crossroad of cancer metastasis.
The expression of CCL2 was increased in AD.
Localization of the CCL2 was revealed by immunohistochemistry.
It is therefore concluded that the same theoretical approach should give reliable simulated CCl2(X1A1) + e <-- CCl2-(X2B1) and CCl2(a3B1) + e <-- CCl2-(X2B1) bands in the photodetachment spectrum ...
CCL2 mRNA and CCL2 protein were highly expressed, but not regulated by E(2) .
The accumulation of subretinal macrophages was enhanced in Ccl2(-/-), but not in Cx3cr1(-/-) or Ccl2(-/-)/Cx3cr1(-/-) mice.
No evidence of toxic effects of CCL2 or CCL2-ethanol interactions was observed.
Both CCL2 and CCL12 are chemotactic for fibrocytes.
CCL2 blockade augments cancer immunotherapy.
CCL2/CCR2: push/pull for migration.
[CCL2 chemokine and transmission of nociceptive information].
In contrast to CCL2, 7ND is an obligate monomer.
This effect of CCL2 was prevented by an antagonist of CCR2.
CCL2(-/-) mice had a deficiency of CCL2 in their BALF and sera post-BMT, confirming our hypothesis that CCL2 is predominantly host derived.
Kinetics of the reactions of O(3P) with CCl2=CH2, (Z)-CHCl=CHCl, and CCl2=CCl2: a temperature dependence study.
Blockage of CCL2 with a neutralized antibody against CCL2 abolished the effects of CCL2 on neural progenitor cell migration and differentiation.
The CCL2-mediated expression of ICAM-1 was significantly reduced by neutralization of CCL2 using a specific CCL2 antibody.
Only CCL2/CCR2 signalling influenced neovascularization, which was increased in mice overexpressing CCL2, whereas it markedly decreased in CCL2-/- mice.
For the photodetachment spectrum of CCl2-, spectral simulation shows that the higher binding energy a3B1(CCl2) <-- X2B1(CCl2-) band is well separated from the X1A1(CCl2) <-- X2B1(CCl2-) band.
It is concluded that the observed second band, which overlaps heavily with the X1A1(CCl2) <-- X2B1(CCl2-) band in the photodetachment spectrum of CCl2- cannot be assigned to the CCl2(a3B1) + e --> ...
Franck-Condon factors including anharmonicity have been calculated, between the CCl2 states, and between the CCl2- X2B1 state and the CCl2 states.
To explore the potential value of serum CCL2 measurement in disease assessment, we have compared CCL2 levels with clinical phenotype and investigated effect of therapy on circulating CCL2.
B16 cells (a murine melanoma cell line) highly expressing CCL2 (CCL2-B16 cells) were obtained by transfection with recombinant plasmid CCL2-pcDNA3.
When considering CCL2 in the parenchyma, the mean survival time for the patients with high CCL2+ cell counts was lower than that for patients with low CCL2+ cell counts.
Focal upregulation of CCL2 within FIX-DeltaUS28-infected cells demonstrated intracellular CCL2 accumulation was independent of CCL2 sequestration by the CMV-encoded chemokine receptor US28.
In addition, we also found that FL- and K104Stop-CCL2 were able to restore the changes found in CCL2(-/-) mice, but K104A-CCL2 failed to do so.
CCL2-null and wild-type mice were exposed to HPC 2 days prior to tMCAo, with immunoneutralization of CCL2 during HPC achieved by a monoclonal CCL2 antibody.
Glycosylation enhances functional stability of the chemotactic cytokine CCL2.
Chemokines in Kawasaki disease: measurement of CCL2, CCL22 and CXCL10.
CCL2 (monocyte chemoattractant protein-1) and cancer.
Similar findings were observed with CCL2 and CCL5.
The relevance of CCL2 production was determined in chemotaxis transmigration assays.
The downregulation of CCL2 production was regulated at different levels.
First, the synthesis of CCL2 mRNA was significantly decreased.
Morphine stimulates CCL2 production by human neurons.
In DM, endothelial expression of CCL2 and CXCL12beta was highly increased.
CCL2 DNA vaccine to treat renal disease.
Macrophages recruited by CCL2 lead to progressive renal injury.
The mechanism of protection involves the induction of auto-antibodies to the CCL2.
There are three ligands for CCR2 in the mouse: CCL2, CCL7, and CCL12.
CCL2 is elevated in the peritoneal fluid of women with endometriosis.
CCL2, a major monocyte chemokine, is upregulated in the AD brain.
Role of CCL2/MCP-1 in islet transplantation.
To measure circulating CXCL10 and CCL2 in cryoglobulinaemic patients.
The inflammatory chemokines CCL2 and CCL5 in breast cancer.
Pathogenic role of CCL2/MCP-1 in scleroderma.
Downregulation of CCL2 also led to a decreased migration of monocytes.
The uptake of Tat was followed by an increase in MCP1 (CCL2) immunoreactivity.
Monocyte recruitment was HIV-1 Tat and CCL2 dependent.
Expression of CCL2 was examined by an enzyme-linked immunosorbent assay.
CCL2, but not CX3CL1 is increased in the airway and blood of CF patients.
This review will discuss these biological processes and the structure and function of CCL2.
CCL2/MCP-1 modulation of microglial activation and proliferation.
Genetic variation at CCL2 is associated with markers of disease aggressiveness.
The results support CCL2 as a candidate biomarker for IPF in dogs.
CCL2 disrupts the adherens junction: implications for neuroinflammation.
Surface localization of PECAM-1 is increased in response to CCL2.
And the rises of CXCL8 and CCL2 are more obvious in the mortality cases.