The assay was standardized for MMP-1, MMP-3, MMP-13, and MMP-14.
Of interest is the enrichment of a majority of MMP members in monocytes: MMP-1, MMP-3, MMP-9, MMP-10, MMP-14, MMP-19 and MMP-25.
Oligonucleotide primers for thirteen MMPs (MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, MMP-14, MMP-15, MMP-16) were optimized for use in RT-PCR.
The main outcome parameters measured included expressions of MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, MMP-14, MMP-16, MMP-23 and MMP-24.
At the initial period of thrombosis, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, and MMP-24 had significantly high expression, while MMP-12, MMP-13, MMP-14, MMP-16 and MMP-23 had relatively ...
Based on local expression pattern of MMPs at the mRNA level, aseptic loose artificial hip joint was characterized by elevated expression of MMP-1, MMP-9, MMP-10, MMP-12, and MMP-13; moderate ...
We identified MMP-1, MMP-2 and MMP-9, but not MMP-3 or MMP-8 in bronchial washings.
We compared the results with the mRNA expression of MMP (MMP-I, MMP-2, MMP-3, MMP-9) studied previously.
Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.
Admixed inflammatory cells were immunoreactive for MMP-1, MMP-2, MMP-7, MMP-9, and MMP-13.
Notably, a significant selectivity for MMP-8, MMP-12, and MMP-13 was observed with respect to MMP-1 and MMP-7.
Selectivity of the probes was demonstrated in vitro using MMP-1, MMP-2, MMP-3, MMP-12, and MMP-13.
MMP-1 and MMP-2 production predominates over that of MMP-9 in effusions.
MMP-2 is activated by a membrane-bound MMP (MT1-MMP).
The expression of MMP-2, matrilysin (MMP-7), MMP-9.
Purified MMP-1, MMP-2, MMP-3, MMP-8, MMP-9 and MMP-13 cleaved human prolactin at Gln157, one residue downstream from the chondrocyte protease cleavage site, with the following relative potency: ...
In the medulla, MMP-9 and MMP-7 were increased, but there was no change in MMP-2.
MMP-1, MMP-2, and MMP-13 also stained mast cells.
Matrix metalloproteinase (MMP)-7 activates MMP-8 but not MMP-13.
MMP-3, MMP-7 and MMP-8 appear to be important in these processes.
Results show that the cells produce MMP-1 and MMP-13 but not MMP-8.
MMP expression was investigated in the aortas by using MMP immunostaining and in situ MMP zymography.
Expression of MMP-2, MMP-9 and MMP-11 in dermatofibroma and dermatofibrosarcoma protuberans.
The enhancement was associated with increasing MMP-2, MMP-9, and MT1-MMP expression.
Cellular sources of MMP-7, MMP-13 and MMP-28 in ulcerative colitis.
MMP-1, MMP-8, or MMP-13 was expressed in macrophages.
MMP-1, MMP-3, MMP-8, MMP-10, MMP-11, and MMP-13 mRNAs were also expressed in some or most of the cell lines.
The expression of MMP-3, MMP-9, and MMP-13 was similar in all four tissues with the predominance of syncytiotrophoblast for MMP-3 and MMP-13 and cytotrophoblast for MMP-9.
AQARSAASKVKVSMKF also induced expression of MMP-14, while MMP-2, MMP-3, MMP-7, MMP-12, and MMP-13 were not induced by this peptide.
Functional polymorphisms in the promoters of MMP-1, MMP-2, MMP-3, MMP-9, MMP-12 and MMP-13 are not associated with hepatocellular carcinoma risk.
This activity was suppressed by the inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9, but not by the inhibitors of MMP-1, MMP-3, MMP-8, and MMP-13.
IL21 enhances fibroblast production of MMP-1, MMP-2, MMP-3 and MMP-9, but not tissue inhibitors of MMP-1 and MMP-2.
We could not detect MMP-2, MMP-3, MMP-7, MMP-10, MMP-11, and MMP-12 by RT-PCR with and without stimulation with LPS.
Novel targets, including MMP-8, MMP-10, MMP-14, MMP-19, MMP-25 and MMP-28, are also being considered.
Activities of MMP-13 and MMP-14 were low.
Molecular imaging of MMP expression and therapeutic MMP inhibition.
The expression of MMP-2 correlated positively with MMP-9.
These synthetic inhibitors are selective for MMP-2 and MMP-9.
MMP-2 and MMP-9 expression in the veins was not enhanced.
MT1-MMP is an MMP anchored to the cell membrane.
To investigate the roles of MMPs in the progression of nasopharyngeal carcinoma (NPC), the expression of MMP-1, MMP-2, MMP-3, MMP-7, MMP-12, MMP-13, MMP-14, and MMP-19 was explored by microarray ...
There was no detective of MMP-2 and MMP-9 in normal retinas.
Serum concentrations of MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-13, and TIMP-1 were determined by ELISA in 54 adult CF patients.
MMP-2 and MMP-9 were examined by immunohistochemistry.